Guidelines to establish relative potency are not in touch with reality

In touch with reality

Objective: A descriptive study in which the audience profile of patients suffering from schizophrenia, their families and caregivers was determined to establish whether information on schizophrenia is disseminated effectively. This is an ongoing project aimed at designing appropriate psychoeducational material on schizophrenia using the audience-based media production approach. Method: A Qualit...

Communicating by touch--neurons are not alone.

Long-distance cell-cell communication is essential for organ development and function. Whereas neurons communicate at long distances by transferring signals at sites of direct contact (i.e., at synapses), it has been presumed that the only way other cell types signal is by dispersing signals through extracellular fluid--indirectly. Recent evidence from Drosophila suggests that non-neuronal cell...

Reality Does Not Recognize Borders

Reality does not recognize borders. Why we should use the very general term of “reality” and not science, because the borders that we draw are pure delusions, and on the opposite side there is the reality. The laws of the universe, either the physical nature of the world which the scientist studies or metaphysics which is the territory of philosophers, it isthe same reality that rules. Today ma...

Germ Cells Are Not Required to Establish the Female Pathway in Mouse Fetal Gonads

The fetal gonad is composed of a mixture of somatic cell lineages and germ cells. The fate of the gonad, male or female, is determined by a population of somatic cells that differentiate into Sertoli or granulosa cells and direct testis or ovary development. It is well established that germ cells are not required for the establishment or maintenance of Sertoli cells or testis cords in the male ...

Relative Potency Estimation in Direct Bioassay with Measurement Errors*